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Side Effects
The most common side effect of orlistat is changes in bowel movement (BM) habits. This generally occurs during the first weeks of treatment; however, it may continue throughout your use of orlistat. T
ell your doctor if any of these symptoms are severe or do not go away:
- oily, spotting BMs
- gas with discharge
- urgent need to have a BM
- oily or fatty stools
- an oi
ly discharge
- increased number of BMs
- inability to control BMs
- orange or brown color of a BM
- stomach pain
-
If you experience any of the following symptoms, c
all your doctor immediately:
- itching
- redness of skin
- skin rash or hives
- swelling
- chest pain
- difficulty breathing
- fever
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Proper Use of This Medicine
Orlistat comes as a capsule to take by mouth. It is usually taken three times a day with each main meal that contains fat. Each time you take orlistat, your meal should contain no more than about 30%
of calories from fat. Take orlistat during or up to 1 hour after a meal. If a meal is missed or does not have fat, you may skip your dose. Follow the directions on your prescription label carefully, a
nd ask your doctor or pharmacist to explain any part you do not understand.
Orlistat is in a class of drugs called lipase inhibitors. It works in your intestines, where it blocks some of the
fat you eat from being absorbed and disgested. This undigested fat is then removed in your bowel movements (BM).
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Why is this drug prescribed?
Orlistat is used with a low-calorie diet to help you lose weight and to maintain your weight after weight loss. Orlistat is used in patients with a certain weight who may also have high blood pressure
, diabetes, high cholesterol, or heart disease.
- Orlistat is in a class of drugs called lipase inhibitors. It works in your intestines, where it blocks some of the fat you eat from being abs
orbed and disgested. This undigested fat is then removed in your bowel movements (BM).
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Other medical problems
Pregnancy¡XOrlistat has not been studied in pregnant women. However, orlistat may decrease the amount of certain vitamins that your body can absorb from the food you eat. Make sure you have discussed
ith your doctor the use of this medication during pregnancy.
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Precautions while Using this Medicine
Follow the diet program your doctor has given you. You should evenly divide your daily intake of fat, carbohydrates, and protein over three main meals. If orlistat is taken with a meal very high in fa
t (30% total daily calories from fat), you may experience more side effects from the medication.
Orlistat blocks your body's uptake of some fat-soluble vitamins and beta carotene. Therefore,
when you use orlistat you should take a daily multivitamin supplement that contains vitamins A, E, K, and beta-carotene. Take the vitamin once a day, 2 hours before or 2 hours after taking orlistat, o
r take the vitamin at bedtime.
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Other Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to c
hange the dose, or other precautions may be necessary. When you are taking orlistat, it is especially important that your health care professional know if you are taking the following:
- Warf
arin¡XOrlistat may decrease the absorption of vitamin K and may change your bleeding time
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