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Other medical problems

Children¡XPaxil has not be shown to be safe and effective in children or adolescents, 18 years of age or younger. Children may be especially sensitive to the effects of Paxil for the treatment of depr ssion. This may increase the chance of a child planning to commit suicide or attempting to commit suicide. Talk to your doctor about the risks and benefits of taking this medication.

Adverse Effects

Nervous System: - Frequent: CNS stimulation, concentration impaired, depression, emotional lability, vertigo. Infrequent: Akinesia, alcohol abuse, amnesia, ataxia, convulsion, depersonalization, hallu cinations, hyperkinesia, hypertonia, incoordination, lack of emotion, manic reaction, paranoid reaction, thinking abnormal. Rare: Abnormal EEG, abnormal gait, antisocial reaction, choreoathetosis, cir cumoral paresthesia, delirium, delusions, diplopia, drug dependence, dysarthria, dyskinesia, dystonia, euphoria, fasciculations, grand mal convulsion, hostility, hyperalgesia, hypokinesia, hysteria, l ibido increased, manic depressive reaction, meningitis, myelitis, neuralgia, neuropathy, nystagmus, psychosis, psychotic depression, reflexes increased, stupor, withdrawal syndrome.

Possible food and drug interactions when taking this medication

Renal Impairment: - Since paroxetine is extensively metabolized by the liver, excretion of unchanged drug in urine is a minor route of elimination. However, single dose pharmacokinetic studies in subj ects with clinically significant renal impairment suggest that plasma levels of paroxetine are elevated in such subjects. Paroxetine should therefore be used with caution and the dosage restricted to the lower end of the range in patients with clinically significant renal impairment.

What special precautions should I follow?

Before taking Paxil,

remember that alcohol can add to the drowsiness caused by this drug.
tell your doctor if you use tobacco products. Cigarette smoking may decrease the effectiveness o f this drug.
plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Paxil may make your skin sensitive to sunlight.

Possible Side Effect

More common side effects may include:
- Abnormal ejaculation, abnormal orgasm, constipation, decreased appetite, decreased sex drive, diarrhea, dizziness, drowsiness, dry mouth, gas, impotence, m ale and female genital disorders, nausea, nervousness, sleeplessness, sweating, tremor, weakness, vertigo

How should this medicine be used?

Paxil has not been shown to add to the effects of alcohol. However, use of alcohol is not recommended in patients who are taking Paxil.

Paxil may cause some people to become drowsy or have bl urred vision. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert or able to see clearly.


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