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Special Wanring
Serious Adverse Reactions: - Suicidal thoughts and acts are far more common among depressed patients than in the general population. It is estimated that suicide is 22 to 36 times more prevalent in de
pressed persons than in the general population. A comprehensive meta-analysis of pooled data from 17 double blind clinical trials in patients with major depressive disorder compared fluoxetine (n=1765
) with a tricyclic antidepressant (n=731) or placebo (n=569), or both. The pooled incidence of emergence of substantial suicidal ideation was 1.2% for fluoxetine, 2.6% for placebo, and 3.6% for tricyc
lic antidepressants.
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Warning
Pregnancy and Lactation: - Safe use of fluoxetine during pregnancy and lactation has not been established. Therefore, it should not be administered to women of childbearing potential or nursing mother
s unless, in the opinion of the treating physician, the expected benefits to the patient markedly outweigh the possible hazards to the child or fetus. In 1 breast milk sample, the concentration of flu
oxetine plus norfluoxetine was 70.4 ng/mL. The concentration in the mother's plasma was 295 ng/mL. No adverse effects on the infant were reported.
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Symptoms of overdose
May be more severe than side effects that may occur from regular doses, or several symptoms may occur together
- Agitation and restlessness; convulsions (seizures); drowsiness; fast heartbeat;
nausea and vomiting; talking, feeling, and acting with excitement and activity you cannot control; trembling or shaking
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Possible Side Effect
If you experience any of the following symptoms, call your doctor immediately:
- jaw, neck, and back muscle spasms
- slow or difficult speech
- shuffling walk
- persistent, fi
ne tremor or inability to sit still
- fever, chills, sore throat, or flu-like symptoms
- difficulty breathing or swallowing
- severe skin rash or hives
- yellowing of the skin or e
yes
- irregular heartbeat
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Other Medicines
Combining Prozac with MAO inhibitors or Mellaril (thioridazine) is dangerous.
Do not drink alcohol while taking this medication.
It is especially important to check with your docto
r before combining Prozac with the following:
- Alprazolam (Xanax)
- Carbamazepine (Tegretol)
- Clozapine (Clozaril)
- Diazepam (Valium)
- Digitoxin (Crystodigin)
-
Drugs that impair brain function, such as sleep aids and narcotic painkillers
- Flecainide (Tambocor)
- Haloperidol (Haldol)
- Lithium (Eskalith)
- Other antidepressants (Elavil) <
br> - Phenytoin (Dilantin)
- Pimozide (Orap)
- Tryptophan
- Vinblastine (Velban)
- Warfarin (Coumadin)
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What is this Drug
Prozac , an antidepressant (mood elevator), is used to treat depression, obsessive-compulsive disorders, and some eating disorders. Prozac (Sarafem) is used to treat premenstrual dysphoric disorder.
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