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Possible Side Effect

Although side effects from Retin-A are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:

- warmth or slight stinging of the skin
- ligh tening or darkening of the skin
- red, scaling skin
- increase in acne sores
- swelling, blistering, or crusting of the skin

How should this medicine be used?

Make sure you tell your doctor if you have any other medical problems, especially:
- Dermatitis, seborrheic or
- Eczema or
- Sunburn¡XUse of this medicine may cause or increase the irr tation associated with these problems

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to c hange the dose, or other precautions may be necessary. Tell your health care professional if you are using any other topical prescription or nonprescription (over-the-counter [OTC]) medicine that is t o be applied to the same area of the skin. When you are using topical Retin-A, it is especially important that your health care professional know if you are taking any of the following:

- Ac itretin (e.g., Soriatane)
- Etretinate (e.g., Tegison)
- Retin-A, oral ¡XMay increase chance of getting severe dryness or redness of skin

What Is It

Retin-A is used to treat acne. It works partly by keeping skin pores clear.

One of the Retin-A creams is used to treat fine wrinkles, dark spots, or rough skin on the face caused by damaging rays of the sun. It works by lightening the skin, replacing older skin with newer skin, and by slowing down the way the body removes skin cells that may have been harmed by the sun. Retin-A works bes t when used within a skin care program that includes protecting the treated skin from the sun. However, it does not completely or permanently erase these skin problems or greatly improve more obvious changes in the skin, such as deep wrinkles caused by sun or the natural aging process.

What special precautions should I follow?

Older adults¡XMany medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause differ nt side effects or problems in older people. There is no specific information comparing use of Retin-A in patients 50 years of age and older with use in other age groups.

Cautions

Unless your doctor tells you otherwise, it is especially important to avoid using the following skin products on the same area as Retin-A:

- Any other topical acne product or skin product co ntaining a peeling agent (such as benzoyl peroxide, resorcinol, salicylic acid, or sulfur)
- Hair products that are irritating, such as permanents or hair removal products
- Skin products th at cause sensitivity to the sun, such as those containing spices or limes
- Skin products containing a large amount of alcohol, such as astringents, shaving creams, or after-shave lotions
- Skin products that are too drying or abrasive, such as some cosmetics, soaps, or skin cleansers


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