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Other Medicines
General Anesthetics: - Since little is known about the interaction between fluoxetine and general anesthetics, fluoxetine should be discontinued for as long as clinically possible prior to elective su
rgery.
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Symptoms of overdose may include:
May be more severe than side effects that may occur from regular doses, or several symptoms may occur together
- Agitation and restlessness; convulsions (seizures); drowsiness; fast heartbeat;
nausea and vomiting; talking, feeling, and acting with excitement and activity you cannot control; trembling or shaking
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Possible food and drug interactions when taking this medication
When you are taking Prozac, it is especially important that your health care professional know if you are taking any of the following:
- Selective serotonin reuptake inhibitors, other (cital
opram [Celexa], fluvoxamine [e.g., Luvox], paroxetine [e.g., Paxil], sertraline [e.g., Zoloft]) or
- Street drugs (LSD, MDMA [e.g., ecstasy], marijuana) or
- Sumatriptan (e.g., Imitrex) or <
br> - Tramadol (e.g., Ultram) or
- Trazodone (e.g., Desyrel) or
- Tryptophan or
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Other medical problems
Older adults¡XMany medicines have not been tested in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effec
s or problems in older people. In studies done to date that included elderly people, Prozac did not cause different side effects or problems in older people than it did in younger adults.
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How should this medicine be used?
Prozac should be taken exactly as prescribed by your doctor.
Prozac usually is taken once or twice a day. To be effective, it should be taken regularly. Make a habit of taking it at the same
time you do some other daily activity.
It may be 4 weeks before you feel any relief from your depression, but the drug's effects should last about 9 months after a 3-month treatment regimen
. For obsessive-compulsive disorder, the full effect may take 5 weeks to appear.
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Precautions
Mania/Hypomania: - During premarketing clinical trials in a patient population comprised primarily of unipolar depressives, hypomania or mania occurred in approximately 1% of fluoxetine treated patien
ts. The incidence in a general patient population which might also include bipolar depressives is unknown. The likelihood of hypomanic or manic episodes may be increased at the higher dosage levels. S
uch reactions require a reduction in dosage or discontinuation of the drug.
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